The short answer, explained
When an HMRC enquiry closes with additional tax due, several things can follow, not just one bill. First is the underpaid tax itself, established through the closure notice or discovery assessment. Second is interest, which accrues from when the tax was originally due, not from when HMRC finished checking.
Third, and often the biggest surprise, is the penalty. This is calculated as a percentage of the tax underpaid, set by your behaviour and how you disclosed the error. Fourth, in a small minority of cases involving dishonesty, HMRC can pursue criminal prosecution instead of, or as well as, the civil penalty regime.
Most enquiries end with tax, interest and a civil penalty, and never come close to the criminal threshold. The behaviour and disclosure elements are where you have the most influence over the final number.

